Quick Verdict
The Transparency Gold Standard — With Caveats
Ancestral Supplements FEM does what most competitors refuse to do: disclose every ingredient amount. You get 1,200mg reproductive tissue (ovary, uterus, fallopian tubes), 900mg liver, and 900mg bone marrow — 3,000mg total daily across 6 capsules. With 33,886 Amazon reviews at 4.5 stars, New Zealand grass-fed sourcing, and no proprietary blend hiding the math, this is the most transparent female beef organ supplement on the market. But transparency alone doesn't equal efficacy. Liver at 900mg is still 15–30% of the clinical range. The "like supports like" principle behind the reproductive organs has zero clinical validation. At $68/month, it's the most expensive option in the category. And the Liver King steroid scandal and FDA scrutiny on the brand are worth weighing.
Key Strengths
- Full ingredient disclosure — gold standard
- 33,886 Amazon reviews at 4.5 stars
- New Zealand grass-fed sourcing
- 3,000mg total daily dose (6 capsules)
- Gradual dosing protocol shows care
Key Concerns
- Liver at 900mg is 15–30% of clinical range
- Zero clinical trials on this product
- "Like supports like" has no peer-reviewed validation
- $68/mo — most expensive in category
- Liver King steroid scandal undermines brand trust
Best For: Health Goal Ratings
Based on Ancestral Supplements FEM's specific ingredients, doses, and clinical evidence, here's how the formula maps to common health goals. Only goals supported by ingredients in the formula are rated.
Health goal ratings are derived from the specific ingredients, doses, and clinical evidence in this product's formula. They reflect formula suitability for each goal — not guaranteed outcomes. A high rating means the formula contains clinically-relevant ingredients at meaningful doses for that goal. Always consult a healthcare provider for specific health conditions.
What Is Ancestral Supplements FEM?
FEM (Female Enhancement Mixture) is a beef organ supplement designed for women, manufactured by Ancestral Supplements LLC in Willis, Texas. Founded by Brian Johnson — better known as "Liver King" — Ancestral Supplements is arguably the most established name in the organ supplement space, having pioneered the category before it became a mainstream wellness trend.
The formula contains three types of organ material sourced from 100% grass-fed New Zealand cattle: reproductive tissue (ovary, uterus, fallopian tubes), liver, and bone marrow. All ingredients are freeze-dried to preserve nutrient content. The product ships in a 180-capsule bottle — a 30-day supply at the recommended 6 capsules per day.
What separates FEM from most competitors immediately is full ingredient disclosure. There is no proprietary blend. Every ingredient amount is printed on the label. This is how supplement labels should work, and it's surprisingly rare in the female organ supplement space.
Ancestral Supplements recommends starting with just 1 capsule per day for the first 3 days, then increasing by 1 capsule every 3 days until you reach the full 6-capsule dose. This 3-week ramp-up is good practice — it allows your body to adjust to concentrated organ nutrients and minimizes digestive discomfort. It also suggests the company understands that organ supplements can cause adjustment effects, which is a mark of honesty.
Ingredient Analysis
FEM contains three ingredients with fully disclosed amounts. This is one of the simplest, most transparent formulas in the female organ supplement market. Let's examine each component.
Full Ingredient Breakdown
| Ingredient | Key Benefits | Effective Dose | FEM Dose | Verdict |
|---|---|---|---|---|
| Grassfed Reproductive Tissue (Ovary, Uterus, Fallopian Tubes) | Hormonal peptides, tissue-specific nutrients | No established dose | 1,200 mg | No clinical benchmark |
| Grassfed Liver (Bovine) | Vitamin A, B12, iron, folate, copper | 3,000–6,000 mg/day | ⚠ 900 mg | 15–30% of effective dose |
| Grassfed Bone Marrow (Bovine) | Collagen, CoQ10, alkylglycerols, fatty acids | 500–3,000 mg/day | 900 mg | 30–100% of effective range |
Component Analysis
Reproductive Tissue (1,200mg): This is the largest component by weight — 40% of the total formula. It combines ovarian, uterine, and fallopian tube tissue. The claimed mechanism is "like supports like": consuming bovine reproductive organs supports your own reproductive system. This principle has roots in traditional medicine and some radioisotope labeling studies from the University of Edinburgh suggest organs can target homologous tissues. However, no peer-reviewed human study has validated this for reproductive organs specifically. The 1,200mg dose is substantial in terms of volume, but there's no established clinical benchmark to compare against.
Liver (900mg): Beef liver is arguably the most nutrient-dense food on the planet — rich in bioavailable vitamin A (retinol), B12, heme iron, folate, and copper. At 900mg, FEM delivers significantly more liver than Primal Queen's estimated ~170–200mg, but it's still only 15–30% of the 3,000–6,000mg range where clinical research shows measurable benefits. This is a meaningful dose — you'll get real nutrients from it — but it's not an optimal one.
Bone Marrow (900mg): The strongest dosing in the formula relative to clinical benchmarks. At 900mg, bone marrow sits comfortably in the 30–100% range of effective doses. Bone marrow is a natural source of collagen, CoQ10, alkylglycerols (immune-supporting lipids), and essential fatty acids. This is the ingredient most likely to deliver tangible benefits at this dose.
Why Full Disclosure Matters
This is the section where Ancestral Supplements FEM genuinely separates itself from the competition. Let's put it in context.
Primal Queen uses a proprietary blend — you don't know how much of each organ you're getting. Glowing Goddess does the same. Goddess Vitality discloses everything (identical formula to FEM). Primal Woman from Wellanova claims "full transparency" but actually uses a proprietary blend. FEM shows every amount on the label. This is how every supplement should operate.
When a supplement hides behind a proprietary blend, it becomes impossible for you, your doctor, or any independent reviewer to evaluate whether the ingredients are present at meaningful doses. Ancestral Supplements doesn't hide. You know you're getting exactly 1,200mg of reproductive tissue, 900mg of liver, and 900mg of bone marrow. Period.
This matters for several practical reasons. If you're tracking your iron intake (liver is high in heme iron), you can calculate it. If your doctor wants to assess interactions, they have the data. If you want to compare value across brands, you can do real math instead of guessing.
We gave FEM a 9.0 for dose transparency — the highest score in this category across every product we've reviewed. The only reason it isn't a 10 is that the reproductive tissue component bundles three organs (ovary, uterus, fallopian tubes) into a single 1,200mg line item. We'd prefer to see each broken out individually, but this is a minor point compared to the industry standard of disclosing nothing.
Does It Work? Clinical Evidence
This is where the score drops. Despite being the most transparent and most-reviewed product in the category, Ancestral Supplements FEM has no product-specific clinical trials. None. Zero.
What the Company Claims
Ancestral Supplements references the "like supports like" principle and cites radioisotope labeling studies from the University of Edinburgh/Scotland suggesting that consumed organs and glands target homologous organs in the body. They also reference general benefits of the peptides and enzymes found in organ meats.
What the Evidence Actually Shows
- Beef liver nutrients are well-documented. Liver is one of the most studied organ meats, rich in vitamin A, B12, iron, and folate. At adequate doses (3,000–6,000mg), desiccated liver supplements have measurable nutritional benefits. At 900mg, you're getting a fraction of those studied doses — real nutrients, but below the clinical threshold.
- Bone marrow has emerging research. Collagen, CoQ10, and alkylglycerols from bone marrow have preliminary evidence for joint health, immune support, and skin quality. The 900mg dose here is within a reasonable range.
- "Like supports like" is unvalidated. No peer-reviewed human study has demonstrated that consuming bovine ovaries supports human ovarian function, or that bovine uterine tissue benefits the human uterus. The radioisotope studies show tissue targeting — not therapeutic benefit. These are different claims.
- No randomized controlled trials. Unlike Primal Queen, which at least commissioned a brand-funded study through Citruslabs, Ancestral Supplements has not published any clinical research on FEM specifically.
The 33,886 Amazon reviews at 4.5 stars represent substantial social proof. Many users report improvements in energy, PMS symptoms, hormonal balance, skin, and hair. These reports are consistent and numerous enough to suggest the product does something for a meaningful percentage of users. But anecdotal evidence — even at massive scale — is not clinical evidence. The placebo effect is real, and self-reported outcomes are inherently subjective.
The Liver King Controversy & FDA Scrutiny
Two issues that don't affect the formula but are relevant to your trust assessment of the brand.
The Steroid Admission (2022)
Brian Johnson, founder of Ancestral Supplements and social media persona "Liver King," built his brand on promoting an ancestral, primal lifestyle — eating raw organ meats, training with primitive equipment, and rejecting modern supplementation. In 2022, leaked emails revealed he had been spending approximately $11,000 per month on anabolic steroids and growth hormone while publicly promoting his physique as the result of organ meats and primal living.
Johnson admitted to the steroid use. The fallout was significant — it undermined the core authenticity of his brand messaging. To be clear: this doesn't mean the beef organs inside FEM capsules are somehow different or lower quality. The New Zealand sourcing, freeze-drying process, and ingredient formulation are independent of the founder's personal choices. But brand trust is a legitimate factor in purchasing decisions, and this event damaged it.
FDA Advisory (April 2025)
In April 2025, the FDA issued an advisory regarding Ancestral Supplements' Beef Thyroid product for making unauthorized drug claims. This advisory was specifically about their thyroid product, not FEM. However, it indicates that the brand is under active regulatory scrutiny, which is relevant context for assessing the company as a whole.
What Customers Are Actually Saying
With 33,886 Amazon reviews at 4.5 stars, FEM is by far the most-reviewed female beef organ supplement on the market. For comparison, Glowing Goddess has 259 reviews and Primal Queen has 835 on Trustpilot. The volume here is in a different league entirely.
Positive Themes
- PMS and menstrual improvement — The most frequently cited benefit. Users report less severe PMS, more regular cycles, and reduced cramping. "PMS much less severe" is a representative comment.
- Energy and mood — Many users describe sustained energy improvements and better emotional stability, likely attributable to the liver's B12, iron, and folate content.
- Skin, hair, and nails — Consistent reports of improved skin clarity, stronger nails, and healthier hair — benefits likely driven by the bone marrow's collagen and the liver's vitamin A.
- Hormonal balance — Users going through perimenopause and menopause report symptom relief, including reduced hot flashes and improved sleep.
- Thyroid support — Some reviewers report improved thyroid lab values, though this may be related to the general nutrient density rather than a specific mechanism.
Negative Themes
- Shipping and fulfillment issues — Multiple Trustpilot complaints describe delayed or non-delivered orders. "Never shipped… auto-sub" and "continue to charge over years" are concerning patterns.
- Unauthorized subscription charges — Reports of being charged for subscriptions users believed they had canceled, and difficulty getting refunds processed.
- Customer service frustrations — Some reviewers describe unresponsive or unhelpful support when attempting to resolve billing or shipping issues.
- Stomach sensitivity — Initial digestive discomfort is common, particularly for users who skip the gradual dosing protocol and start at the full 6-capsule dose.
- Price complaints — At $68 per month, many users feel the product is overpriced relative to alternatives with similar or identical formulas.
Pricing & Value Analysis
At $68 per month (or $57.80 with subscription), FEM is the most expensive female beef organ supplement in the category. This is particularly notable because Goddess Vitality — which contains the identical formula manufactured by the same company — sells for approximately $59. You're paying roughly $9 more per month for the Ancestral Supplements brand name on an identical product.
The value equation is mixed. You get full transparency, NZ sourcing, and 3,000mg total daily — meaningful advantages over Primal Queen's ~1,000–1,200mg in a proprietary blend. But you're paying a brand premium that doesn't translate to a formula difference. The quality is genuine; the price reflects brand positioning more than ingredient cost.
Multiple customer reports cite difficulties canceling subscriptions and unauthorized recurring charges. If you subscribe, document your enrollment date and cancellation policy. The 15% discount is meaningful, but monitor your billing carefully.
Ancestral Supplements FEM vs. Alternatives
How does FEM compare to the other female beef organ supplements on the market?
| Feature | Ancestral FEM | Primal Queen | Glowing Goddess | Goddess Vitality |
|---|---|---|---|---|
| Price (Monthly) | $68 ($57.80 sub) | $44 | $29.99 sub | ~$59 |
| Ingredient Transparency | Fully disclosed | Proprietary blend | Proprietary blend | Fully disclosed |
| Total Daily Dose | 3,000 mg (6 caps) | ~1,000–1,200 mg (2 caps) | 675 mg (2 caps) | 3,000 mg (6 caps) |
| Sourcing | NZ grass-fed | Argentina grass-fed | Australia (claimed) | Grass-fed (claimed) |
| Number of Organs | 3 (repro tissue, liver, bone marrow) | 6 (liver, heart, kidney, uterus, fallopian, ovary) | 9–10 organs | 3 (identical to FEM) |
| Amazon Reviews | 33,886 (4.5★) | 835 Trustpilot | 259 (4.1★) | Limited |
| Clinical Trials | None | Brand-funded | None | None |
| Our Rating | 6.5/10 | 2.5/10 | 3.5/10 | 6.0/10 |
The standout comparison is FEM vs. Goddess Vitality. They are the same product — identical ingredients, identical doses, same manufacturer (Ancestral Supplements LLC). Goddess Vitality costs approximately $9 less per month. If formula quality is your only concern, Goddess Vitality is the better value. If brand reputation, NZ sourcing verification, and the Ancestral Supplements ecosystem matter to you, FEM is the known quantity with 33,886 reviews behind it.
Compared to Primal Queen and Glowing Goddess, FEM wins on transparency, total dose, and customer satisfaction — but loses on price. Heart & Soil (founded by Dr. Paul Saladino) offers similar quality and full disclosure at comparable prices, but their formulas are not female-specific.
Full Pros & Cons
Pros
- Full ingredient disclosure — every amount on the label
- 33,886 Amazon reviews at 4.5 stars — massive social proof
- 3,000mg total daily dose across 6 capsules
- 100% grass-fed, New Zealand sourced
- Freeze-dried to preserve nutrients
- Non-GMO, no fillers or flow agents
- Gradual dosing protocol minimizes adjustment issues
- Established brand with deep product line
Cons
- $68/month — most expensive in category
- Liver at 900mg is 15–30% of the 3,000–6,000mg clinical range
- Zero product-specific clinical trials
- "Like supports like" for reproductive organs has no peer-reviewed validation
- Identical formula to Goddess Vitality at ~$9 more per month
- Founder's steroid scandal damaged brand credibility
- FDA advisory on sibling product (Beef Thyroid) shows regulatory scrutiny
- Trustpilot complaints about shipping delays and subscription billing
- 6 capsules daily is a lot to swallow
Frequently Asked Questions
Effectively, yes. Both contain identical ingredients at identical doses: 1,200mg grassfed reproductive tissue (ovary, uterus, fallopian tubes), 900mg liver, and 900mg bone marrow — 3,000mg total daily. Both are manufactured by Ancestral Supplements LLC in Willis, TX. Goddess Vitality is sold under the Optimal Carnivore brand at approximately $59, while FEM is $68. You're paying about $9 more per month for the Ancestral Supplements brand name. The formula is the same.
Reported side effects include stomach discomfort (especially when starting at the full 6-capsule dose — hence the gradual dosing protocol), hormonal shifts during the adjustment period, and occasional breakouts. Organ meats are high in heme iron and vitamin A, so users with iron overload conditions or sensitivity to retinol should exercise caution. The gradual dosing protocol — start at 1 capsule, increase by 1 every 3 days — is designed to minimize these adjustment issues. If symptoms persist beyond the ramp-up period, discontinue use and consult your healthcare provider.
They differ fundamentally on transparency. FEM discloses every ingredient amount (1,200mg reproductive tissue, 900mg liver, 900mg bone marrow). Primal Queen uses a proprietary blend that hides individual doses. FEM delivers 3,000mg total daily in 6 capsules; Primal Queen delivers roughly 1,000–1,200mg in 2 capsules split across 6 organs — approximately 170–200mg per organ. FEM costs more ($68 vs $44), but you know exactly what you're getting. Primal Queen includes heart and kidney (which FEM does not) but at doses too small to be clinically meaningful. For transparency and dose volume, FEM wins. For convenience and price, Primal Queen is cheaper — but you're buying a black box.
There are no clinical trials on FEM specifically. The 33,886 Amazon reviews at 4.5 stars represent substantial social proof — many users report improvements in energy, PMS symptoms, mood, and hormonal balance. The liver and bone marrow components provide real, well-documented nutrients (vitamin A, B12, iron, collagen, CoQ10). However, liver at 900mg is still 15–30% of the 3,000–6,000mg clinical range, and the "like supports like" principle for reproductive organs has never been validated in peer-reviewed human studies. Results likely vary significantly by individual. The product delivers real nutrients at meaningful (if not optimal) doses — which is more than most competitors can say.
The steroid admission was a credibility blow — Brian Johnson promoted a "primal" lifestyle while using performance-enhancing drugs. However, the product itself is independently manufactured, sourced from New Zealand grass-fed cattle, and the ingredient amounts are fully disclosed (unlike many competitors). The formula quality is separate from the founder's personal choices. In April 2025, the FDA issued an advisory for their Beef Thyroid product (not FEM) regarding drug claims, which suggests ongoing regulatory scrutiny. The products are real and well-sourced; the brand trust is a personal judgment call.
With 33,886 Amazon reviews at 4.5 stars, FEM is the most-reviewed female beef organ supplement by a massive margin. Positive themes include PMS reduction, energy improvements, better mood, improved skin and hair, and hormonal balance — especially during perimenopause. Negative themes include stomach sensitivity (especially when skipping the gradual dosing protocol), high price complaints, and Trustpilot reports of shipping delays, unauthorized subscription charges, and refund difficulties. The volume and consistency of positive Amazon reviews is genuinely impressive, even accounting for some review inflation.
Our Final Verdict
Ancestral Supplements FEM earns a 6.5 out of 10 — the highest score we've given to a female beef organ supplement. That score reflects genuine strengths: full ingredient disclosure, NZ grass-fed sourcing, a meaningful 3,000mg daily dose, and 33,886 Amazon reviews at 4.5 stars. This is the transparency gold standard in a category plagued by proprietary blends and hidden math.
But a 6.5 is not an 8 or a 9. The evidence gaps are real. No clinical trials. No peer-reviewed validation for the "like supports like" mechanism that justifies the reproductive organ component (40% of the formula). Liver at 900mg — while genuinely better than Primal Queen's estimated ~170–200mg — is still a fraction of the 3,000–6,000mg range where research shows measurable impact.
The brand carries baggage. The Liver King steroid admission was a significant trust breach. The FDA advisory on their thyroid product signals regulatory attention. Trustpilot complaints about shipping and subscription billing suggest operational issues that a company at this price point shouldn't have.
And then there's the value question. Goddess Vitality sells the identical formula — same ingredients, same doses, same manufacturer — for approximately $9 less per month. If you want this exact product at a better price, it exists.
Still, in a market where most competitors won't even tell you what's in the bottle, Ancestral Supplements FEM stands out by doing the bare minimum that every supplement should: showing you the label. That shouldn't be exceptional, but right now, it is.